N-Benzyloxycarbonyl-6-aminohexanoic acid

N-Benzyloxycarbonyl-6-aminohexanoic acid - Names and Identifiers

Name	N-CARBOBENZOXY-EPSILON-AMINOCAPROIC ACID
Synonyms	N-CBZ-6-AMINOCAPROIC ACID N-CBZ-6-AMINOHEXANOIC ACID N-BENZYLOXYCARBONYL-6-AMINOCAPROIC ACID N-EPSILON-CBZ-EPSILON-AMINOCAPROIC ACID 6-{[(benzyloxy)carbonyl]amino}hexanoate N-BENZYLOXYCARBONYL-6-AMINOHEXANOIC ACID N-CARBOBENZOXY-EPSILON-AMINOCAPROIC ACID N-GAMMA-CARBOBENZOXY-6-AMINOHEXANOIC ACID N-EPSILON-CARBOBENZOXY-6-AMINOCAPROIC ACID 6-{[(benzyloxy)carbonyl]amino}hexanoic acid
CAS	1947-00-8
EINECS	217-748-0
InChI	InChI=1/C14H19NO4/c16-13(17)9-5-2-6-10-15-14(18)19-11-12-7-3-1-4-8-12/h1,3-4,7-8H,2,5-6,9-11H2,(H,15,18)(H,16,17)/p-1

N-Benzyloxycarbonyl-6-aminohexanoic acid - Physico-chemical Properties

Molecular Formula	C14H19NO4
Molar Mass	265.3
Density	1.162±0.06 g/cm3 (20 ºC 760 Torr)
Melting Point	54-57°C(lit.)
Boling Point	408.52°C (rough estimate)
Flash Point	>230°F
Solubility	DMSO (Slightly), Methanol (Slightly)
Vapor Presure	1.41E-09mmHg at 25°C
Appearance	White solid
Color	White to Off-White
BRN	2288508
pKa	4.76±0.10(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.5110 (estimate)
MDL	MFCD00004423
Physical and Chemical Properties	Storage Conditions:? 20℃ WGK Germany:3

N-Benzyloxycarbonyl-6-aminohexanoic acid - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3

N-Benzyloxycarbonyl-6-aminohexanoic acid - Introduction

N-benzyloxycarbonyl-6-aminocaproic acid, also known as Boc-Boc-L-amino-hexanoic acid, is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance is white crystal or crystalline powder.
-The molecular formula is C14H25NO4 and the relative molecular mass is 271.36.
-High thermal and chemical stability.
-It is solid at room temperature and soluble in many organic solvents such as methanol, chloroform and dimethylformamide.

Use:
-n-benzyloxycarbonyl-6-aminocaproic acid is commonly used in the field of organic synthesis, especially as a protecting group in polypeptide synthesis.
-It can be used to construct polypeptides with specific amino acid sequences for research on biochemistry and drug development.
-In addition, it can also be used to synthesize other compounds or drugs.

Method:
-n-benzyloxycarbonyl-6-aminocaproic acid is usually prepared by chemical synthesis.
-A common preparation method is to react pasteuramine with benzyl chlorinating agent to produce N-benzyl pasteuramine, and then treat it with methanol and dimethylformamide, treatment with dilute sulfuric acid gave n-benzyloxycarbonyl-6-aminocaproic acid.

Safety Information:
-n-Benzyloxycarbonyl-6-aminocaproic acid is basically stable and safe under general operating conditions.
-During use and storage, it is necessary to avoid contact with strong oxidants and strong acids.
-During operation, appropriate personal protective measures should be taken, such as wearing gloves, safety glasses and protective clothing.
-In any case, it should be operated in accordance with the laboratory's safe operating procedures.

Last Update：2024-04-09 02:00:43